Monovisc (1x4ml)

Description

MONOVISC 4ml is a treatment used by doctors to alleviate osteoarthritis pain in the knee joint. Here’s an overview of its composition, usage, precautions, and potential side effects:

Composition and Mechanism of Action

• Active Ingredient: MONOVISC contains natural hyaluronan, a glycosaminoglycan that is a major component of synovial fluid in joints.
• Formulation: It is a sterile, non-pyrogenic, viscoelastic solution of ultra-pure hyaluronan.
• Function: When injected directly into the knee joint affected by osteoarthritis, hyaluronan acts as a lubricant and cushion. It replaces and supplements the degraded synovial fluid, which helps reduce pain and improve joint mobility.

Indications and Usage

• Medical Purpose: MONOVISC is specifically indicated for the management of knee osteoarthritis, particularly for patients who have not responded adequately to conservative non-pharmacologic therapy or simple analgesics.
• Administration: The injection should be administered by a qualified healthcare professional.
• Dosage: Each prefilled syringe contains 4ml of the solution and is intended for single use only. The injection procedure typically takes a few minutes and is generally well-tolerated.

Precautions and Contraindications

• Allergies: Do not use MONOVISC if the patient has known allergies to hyaluronate products or to gram-positive bacterial proteins.
• Medical Conditions: It should not be used in patients with active infections or diseases affecting the knee joint, or those with systemic bleeding disorders.
• Handling: The syringe should be used immediately after opening and should not be resterilized. It should not be used if the package is opened or damaged.
• Storage: Avoid freezing the product.

Side Effects

• Common Side Effects: These may include temporary discomfort such as arthralgia (joint pain), injection site pain, joint swelling, muscle cramps.
• Less Common Side Effects: Rash, headache, nausea, dizziness, itching.
• Severe Reactions: While rare, severe allergic reactions can occur. Immediate medical attention should be sought if there are signs of an allergic response such as difficulty breathing, swelling of the face, lips, tongue, or throat.

Post-Injection Care

• Recovery: Patients are typically advised to avoid strenuous activities for about 48 hours post-injection.
• Resumption of Activities: Normal daily activities can usually be resumed thereafter, as guided by the healthcare provider.

Conclusion

MONOVISC 4ml is a sterile and effective treatment option for managing knee osteoarthritis pain by providing lubrication and cushioning to the joint. It is crucial to follow medical advice regarding its use, especially concerning allergies, storage, handling, and post-injection care to ensure optimal outcomes and minimize risks.